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2 Synonyms in 1 Sentence/ A comma before "and"

Hi everyone, 
I’m wondering whether it looks well-written and, most importantly, grammatically correct to use 2 synonyms at once in my following sentence: 
Pacemaker Cells make up only about 1% of the total number of cardiac muscle cells and constitute the cardiac conduction system.
If it looks well-written and is grammatically correct when the audience read it, do you recommend me using a ‘comma’ after ‘muscle cells’ to prevent it from sounding too long for a sentence? 
Pacemaker Cells make up only about 1% of the total number of cardiac muscle cells, and constitute the cardiac conduction system.
Original Quote: 
‘Pacemaker cells make up only about 1% of the total number of cardiac muscle cells. There are three populations of these cells in the heart that are capable of spontaneously generating action potentials and setting the pace of the heart. These three cell populations are collectively called the cardiac conduction system. After looking at how pacemaker cells generate action potentials, we’ll cover the components of the cardiac conduction system’ (Amerman 2019).
Thank you!
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